Splenomegaly (enlarged spleen) is common in thalassemia major and intermedia due to the high rate of hemolysis (red blood cell destruction). The spleen detects the defective red cells of the thalassemic as deficient and removes these from the circulation. The hyperactivity of the spleen results in splenomegaly. The enlarged spleen may be accompanied by an enlarged liver.
Splenomegaly in thalassemia
19 August 2018
The thalassemias are a group of genetically (inherited) blood disorders that share in common one feature; the defective production of hemoglobin which is the protein...