Neonatal Cholestasis
Neonatal Cholestasis
Prognosis of cholestasis due to specific disorders (as for example a metabolic disease) is variable, ranging from a completely benign course to a progressive disease resulting in cirrhosis.
Biliary atresia is progressive and, if untreated, results in liver failure, cirrhosis with portal hypertension by several months of age, and death by 1 yr of age. (2015, J Zagory)
Idiopathic neonatal hepatitis syndrome usually resolves slowly, but permanent liver damage may result and lead to liver failure and death.
1968-7 Bilirubin.direct [Mass/volume] in Serum or Plasma
1975-2 Bilirubin.total [Mass/volume] in Serum or Plasma
ICD-10-CM Code P78.89 Other specified perinatal digestive system disorders
Alagille Syndrome
Alagille syndrome is a multisystem disorder possibly affecting :
- liver: chronic cholestasis due to paucity of intrahepatic bile ducts,
- heart: peripheral pulmonary artery...
Investigations of serum bilirubin are indicated in the first days of life when yellowness rapid appears.
And when the child remains to have a yellow...
Neonatal jaundice is a yellowish discolouration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. The...