Neonatal Cholestasis

Neonatal Cholestasis 

Prognosis of cholestasis due to specific disorders (as for example a metabolic disease) is variable, ranging from a completely benign course to a progressive disease resulting in cirrhosis.

Biliary atresia is progressive and, if untreated, results in liver failure, cirrhosis with portal hypertension by several months of age, and death by 1 yr of age. (2015, J Zagory)

Idiopathic neonatal hepatitis syndrome usually resolves slowly, but permanent liver damage may result and lead to liver failure and death.  

Last modified
28 August 2019

1968-7 [Mass/volume] in Serum or Plasma

1975-2 [Mass/volume] in Serum or Plasma


ICD-10-CM Code P78.89 Other specified perinatal digestive system disorders

Rare Condition

Alagille Syndrome

Alagille syndrome is a multisystem disorder possibly affecting :

- liver: chronic cholestasis due to paucity of intrahepatic bile ducts, 

- heart: peripheral pulmonary artery...


Investigations of serum bilirubin are indicated in the first days of life when yellowness rapid appears.

And when the child remains to have a yellow...

Neonatal jaundice is a yellowish discolouration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels.  The...

General Medical Guideline