The most frequent and typical presentation of rickets is bowing of the long bones, especially leg bowing. Bowing of the bone manifests from the age of 6 months. In those patients, pediatricians and/or orthopedic surgeons are often the first specialists that are consulted. As a certain degree of leg bowing in toddlers is considered physiological, the first consultation may not always lead to a diagnostic work-up and therefore diagnosis is delayed until symptoms worsen. Diagnosis is generally based on blood tests finding low serum phosphorus, and a high or normal alkaline phosphatase together with X-rays.
Leg bowing in rickets
Last modified
29 July 2019
LOINC
Phosphate [Mass/volume] in Serum or Plasma
HPO
Progressive Leg Bowing
Feature
Leg bowing in children is common and often developmental. Neonates and infants often have angulation changes at the knee that gradually corrects within 6 months of...
Rare Condition
X Linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is known as the most common hereditary metabolic rickets with a prevalence of 1:20,000- 60,000. Manifestations are bone deformities (particularly bowing of...
Disease
Hypophosphatemic (HPP) rickets are disorders related to low levels of...