Neonatal screening hemoglobinopathy
For hemoglobinopathies, neonatal screening can be performed by high-performance liquid chromatography (HPLC). The height of the peak of the different hemoglobin types will reveal an indication for sickle cell disease, β thalassemia, Hemoglobin H disease (HbH) or sickle cell disease carriers.
Last modified
30 May 2019
Symptom
Β thalassemia screening by HPLC pattern. When β thalassemia is suspected usually additional tests are performed to confirm the diagnosis. Ultimately it would be best...
When sickle cell disease is suspected by the HPLC pattern usually additional tests are performed to confirm the diagnosis. Ultimately it would be best to...
Rare Condition
Sickle Cell Disease
Sickle cell disease (SCD) is a red blood cell disease, a complex inherited disorder with multisystem manifestations that requires specialized comprehensive care to achieve an optimal...
Thalassemia major or Beta Thalassemia
The thalassemias are a group of genetically (inherited) blood disorders that share in common one feature; the defective production of hemoglobin which is the protein...
