Creatine-kinase in plasma or serum

Creatine-kinase (CK; in the past named creatine-fosfokinase (CPK)) is an important enzyme in the energy chain of the cell.  

Necrosis of cells causing increased permeability of cell membrane or a reduced renal clearance may lead to elevated CK- activity in serum. 

In practice it usually concerns disease of skelet- or heart muscles  Many neuromuschlar diseases are accompanied by an elevated serum CK activity.

Last modified
25 August 2019
Symptom
In Duchenne Muscular Dystrophy, Creatine Kinase is elevated 10–100 times the normal level since birth. This is often accompanied by increased transaminases, which are produced...
Rare Condition

Duchenne Muscular Dystrophy

Duchenne muscular dystrophy is an inherited, X-linked disease that affects about 1 in 3500 - 6000 males. DMD occurs as a result of a change...